UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C.  20549

 

 

SCHEDULE 13G

(Rule 13d-102)

 

Information Statement Pursuant to Rules 13d-1 and 13d-2

Under the Securities Exchange Act of 1934

(Amendment No.  )*

 

 

 

Alexion Pharmaceuticals, Inc.

 

 

(Name of Issuer)

 

 

 

 

 

Common Stock

 

 

(Title of Class of Securities)

 

 

 

 

 

 

 

 

 

015351109

 

 

 

(CUSIP Number)

 

 

 

 

 

 

 

 

 

November 21, 2005

 

 

 

Date of Event Which Requires Filing of the Statement

 

 

 

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

 

[   ]          Rule 13d-1(b)
[X]          Rule 13d-1(c)
[   ]          Rule 13d-1(d)

 

*The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

 

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

Page 1 of 14



 

CUSIP NO. 015351109

13G

Page 2 of 14 Pages

 

 

1.

NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Citadel Limited Partnership

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

 

 

(a)

ý

 

 

(b)

o

3.

SEC USE ONLY

4.

CITIZENSHIP OR PLACE OF ORGANIZATION
Illinois limited partnership

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

5.

SOLE VOTING POWER
0

6.

SHARED VOTING POWER

1,940,704 shares

7.

SOLE DISPOSITIVE POWER
0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
See Row 6 above.

10.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES

 

CERTAIN SHARES

o

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

Approximately 6.3% as of the date of this filing


12.

TYPE OF REPORTING PERSON

 

PN; HC

 

Page 2 of 14



 

CUSIP NO. 015351109

13G

Page 3 of 14 Pages

 

 

1.

NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Citadel Investment Group, L.L.C.

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

 

 

(a)

ý

 

 

(b)

o

3.

SEC USE ONLY

4.

CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware limited liability company

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

5.

SOLE VOTING POWER
0

6.

SHARED VOTING POWER

1,940,704 shares

7.

SOLE DISPOSITIVE POWER
0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
See Row 6 above.

10.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES

 

CERTAIN SHARES

o

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

Approximately 6.3% as of the date of this filing

12.

TYPE OF REPORTING PERSON

 

OO; HC

 

Page 3 of 14



 

CUSIP NO. 015351109

13G

Page 4 of 14 Pages

 

 

1.

NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Kenneth Griffin

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

 

 

(a)

ý

 

 

(b)

o

3.

SEC USE ONLY

4.

CITIZENSHIP OR PLACE OF ORGANIZATION
U.S. Citizen

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

5.

SOLE VOTING POWER
0

6.

SHARED VOTING POWER

1,940,704 shares

7.

SOLE DISPOSITIVE POWER
0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
See Row 6 above.

10.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES

 

CERTAIN SHARES

o

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

Approximately 6.3% as of the date of this filing

12.

TYPE OF REPORTING PERSON

 

IN; HC

 

Page 4 of 14



 

CUSIP NO. 015351109

13G

Page 5 of 14 Pages

 

 

1.

NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Citadel Wellington LLC

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

 

 

(a)

ý

 

 

(b)

o

3.

SEC USE ONLY

4.

CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware limited liability company

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

5.

SOLE VOTING POWER
0

6.

SHARED VOTING POWER

1,940,704 shares

7.

SOLE DISPOSITIVE POWER
0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
See Row 6 above.

10.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES

 

CERTAIN SHARES

o

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

Approximately 6.3% as of the date of this filing

12.

TYPE OF REPORTING PERSON

 

OO; HC

 

Page 5 of 14



 

CUSIP NO. 015351109

13G

Page 6 of 14 Pages

 

 

1.

NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Citadel Kensington Global Strategies Fund Ltd.

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

 

 

(a)

ý

 

 

(b)

o

3.

SEC USE ONLY

4.

CITIZENSHIP OR PLACE OF ORGANIZATION
Bermuda company

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

5.

SOLE VOTING POWER
0

6.

SHARED VOTING POWER

1,940,704 shares

7.

SOLE DISPOSITIVE POWER
0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
See Row 6 above.

10.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES

 

CERTAIN SHARES

o

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

Approximately 6.3% as of the date of this filing

12.

TYPE OF REPORTING PERSON

 

CO; HC

 

Page 6 of 14



 

CUSIP NO. 015351109

13G

Page 7 of 14 Pages

 

 

1.

NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Citadel Equity Fund Ltd.

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

 

 

(a)

ý

 

 

(b)

o

3.

SEC USE ONLY

4.

CITIZENSHIP OR PLACE OF ORGANIZATION
Cayman Islands company

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

5.

SOLE VOTING POWER
0

6.

SHARED VOTING POWER

1,940,704 shares

7.

SOLE DISPOSITIVE POWER
0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
See Row 6 above.

10.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES

 

CERTAIN SHARES

o

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

Approximately 6.3% as of the date of this filing

12.

TYPE OF REPORTING PERSON

 

CO

 

Page 7 of 14



 

CUSIP NO. 015351109

13G

Page 8 of 14 Pages

 

 

1.

NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Citadel Derivatives Group LLC

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

 

 

(a)

ý

 

 

(b)

o

3.

SEC USE ONLY

4.

CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware limited liability company

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

5.

SOLE VOTING POWER
0

6.

SHARED VOTING POWER

1,940,704 shares

7.

SOLE DISPOSITIVE POWER
0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
See Row 6 above.

10.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES

 

CERTAIN SHARES

o

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

Approximately 6.3% as of the date of this filing

12.

TYPE OF REPORTING PERSON

 

OO; BD

 

Page 8 of 14



 

CUSIP NO. 015351109

13G

Page 9 of 14 Pages

 

 

1.

NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Citadel Credit Products Ltd.

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

 

 

(a)

ý

 

 

(b)

o

3.

SEC USE ONLY

4.

CITIZENSHIP OR PLACE OF ORGANIZATION
Cayman Islands company

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH

5.

SOLE VOTING POWER
0

6.

SHARED VOTING POWER

1,940,704 shares

7.

SOLE DISPOSITIVE POWER
0

8.

SHARED DISPOSITIVE POWER

See Row 6 above.

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
See Row 6 above.

10.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES

 

CERTAIN SHARES

o

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

Approximately 6.3% as of the date of this filing

12.

TYPE OF REPORTING PERSON

 

CO; HC

 

Page 9 of 14



 

CUSIP NO. 015351109

13G

Page 10 of 14 Pages

 

 

Item 1(a)

Name of Issuer:  ALEXION PHARMACEUTICALS, INC.

1(b)

Address of Issuer’s Principal Executive Offices:

 

 

 

 

 

352 Knotter Drive

 

 

Cheshire, CT 06410

 

 

 

Item 2(a)

Name of Person Filing

Item 2(b)

Address of Principal Business Office

Item 2(c)

Citizenship

 

 

 

 

 

Citadel Limited Partnership

 

 

131 S. Dearborn Street

 

 

32nd Floor

 

 

Chicago, Illinois 60603

 

 

Illinois limited partnership

 

 

 

 

 

Citadel Investment Group, L.L.C.

 

 

131 S. Dearborn Street

 

 

32nd Floor

 

 

Chicago, Illinois 60603

 

 

Delaware limited liability company

 

 

 

 

 

Kenneth Griffin

 

 

131 S. Dearborn Street

 

 

32nd Floor

 

 

Chicago, Illinois 60603

 

 

U.S. Citizen

 

 

 

 

 

Citadel Wellington LLC

 

 

c/o Citadel Investment Group, L.L.C.

 

 

131 S. Dearborn Street

 

 

32nd Floor

 

 

Chicago, Illinois 60603

 

 

Delaware limited liability company

 

Page 10 of 14



 

CUSIP NO. 015351109

13G

Page 11 of 14 Pages

 

 

 

 

Citadel Kensington Global Strategies Fund Ltd.

 

 

c/o Citadel Investment Group, L.L.C.

 

 

131 S. Dearborn Street

 

 

32nd Floor

 

 

Chicago, Illinois 60603

 

 

Bermuda company

 

 

 

 

 

Citadel Equity Fund Ltd.

 

 

c/o Citadel Investment Group, L.L.C.

 

 

131 S. Dearborn Street

 

 

32nd Floor

 

 

Chicago, Illinois 60603

 

 

Cayman Islands company

 

 

 

 

 

Citadel Derivatives Group LLC

 

 

c/o Citadel Investment Group, L.L.C.

 

 

131 S. Dearborn Street

 

 

32nd Floor

 

 

Chicago, Illinois 60603

 

 

Delaware limited liability company

 

 

 

 

 

Citadel Credit Products Ltd.

 

 

c/o Citadel Investment Group, L.L.C.

 

 

131 S. Dearborn Street

 

 

32nd Floor

 

 

Chicago, Illinois 60603

 

 

Cayman Islands company

 

 

 

2(d)

Title of Class of Securities:

 

 

 

 

Common Stock, par value $.0001 per share

 

 

2(e)

CUSIP Number:

015351109

 

 

Item 3

If this statement is filed pursuant to Rules 13d-1(b), or 13d-2(b) or (c), check whether the person filing is a:

 

 

 

(a)

[__]

Broker or dealer registered under Section 15 of the Exchange Act;

 

 

 

 

 

(b)

[__]

Bank as defined in Section 3(a)(6) of the Exchange Act;

 

 

 

 

 

(c)

[__]

Insurance company as defined in Section 3(a)(19) of the Exchange Act;

 

 

 

 

 

(d)

[__]

Investment company registered under Section 8 of the Investment Company Act;

 

 

 

 

 

(e)

[__]

An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E);

 

Page 11 of 14



 

CUSIP NO. 015351109

13G

Page 12 of 14 Pages

 

 

 

(f)

[__]

An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F);

 

 

 

 

 

(g)

[__]

A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G);

 

 

 

 

 

(h)

[__]

A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act;

 

 

 

 

 

(i)

[__]

A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act;

 

 

 

 

 

(j)

[__]

Group, in accordance with Rule 13d-1(b)(1)(ii)(J).

 

 

 

 

If this statement is filed pursuant to Rule 13d-1(c), check this box.  ý

 

Item 4

Ownership:

 

CITADEL LIMITED PARTNERSHIP

CITADEL INVESTMENT GROUP, L.L.C.

KENNETH GRIFFIN

CITADEL WELLINGTON LLC

CITADEL KENSINGTON GLOBAL STRATEGIES FUND LTD.

CITADEL EQUITY FUND LTD.

CITADEL DERIVATIVES GROUP LLC

CITADEL CREDIT PRODUCTS LTD.

 

(a)

Amount beneficially owned:

 

 

1,940,704 shares

 

(b)

Percent of Class:

 

 

Approximately 6.3% as of the date of this filing

 

 

(c)

Number of shares as to which such person has:

 

 

 

(i)

sole power to vote or to direct the vote:

 

 

 

 

 

0

 

 

 

 

(ii)

shared power to vote or to direct the vote:

 

 

 

 

 

See Item 4(a) above.

 

 

 

 

(iii)

sole power to dispose or to direct the disposition of:

 

 

 

 

 

0

 

 

 

 

(iv)

shared power to dispose or to direct the disposition of:

 

Page 12 of 14



 

CUSIP NO. 015351109

13G

Page 13 of 14 Pages

 

 

 

 

See Item 4(a) above.

 

 

 

Item 5

Ownership of Five Percent or Less of a Class:

 

 

 

 

Not Applicable.

 

 

 

Item 6

Ownership of More than Five Percent on Behalf of Another Person:

 

 

 

 

Not Applicable.

 

 

 

Item 7

Identification and Classification of the Subsidiary which Acquired the Security Being Reported on by the Parent Holding Company:

 

 

 

 

See Item 2 above.

 

 

 

Item 8

Identification and Classification of Members of the Group:

 

 

 

 

Not Applicable.

 

 

 

Item 9

Notice of Dissolution of Group:

 

 

 

 

Not Applicable.

 

 

 

Item 10

Certification:

 

 

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

 


* Mathew B. Hinerfeld is signing on behalf of Kenneth Griffin as attorney-in-fact pursuant to a power of attorney previously filed with the Securities and Exchange Commission on February 4, 2005, and hereby incorporated by reference herein.  The power of attorney was filed as an attachment to a filing by Citadel Limited Partnership on Schedule 13G/A for Komag, Incorporated.

 

Page 13 of 14



 

CUSIP NO. 015351109

13G

Page 14 of 14 Pages

 

After reasonable inquiry and to the best of its knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct.

 

Dated this 30th day of November, 2005

 

KENNETH GRIFFIN

 

CITADEL KENSINGTON GLOBAL

 

 

STRATEGIES FUND LTD.

By:

/s/ Matthew B. Hinerfeld

 

 

 

 

Matthew B. Hinerfeld, attorney-in-fact*

 

 

By:

Citadel Limited Partnership,

 

 

 

 

 

 

its Portfolio Manager

 

CITADEL INVESTMENT GROUP, L.L.C.

 

 

 

 

 

 

 

 

By:

Citadel Investment Group, L.L.C.,

 

By:

/s/ Matthew B. Hinerfeld

 

 

 

its General Partner

 

 

Matthew B. Hinerfeld, Managing

 

 

 

 

 

 

Director and Deputy General Counsel

 

 

By:

/s/ Matthew B. Hinerfeld

 

 

 

 

 

 

Matthew B. Hinerfeld, Managing

 

CITADEL LIMITED PARTNERSHIP

 

 

 

Director and Deputy General Counsel

 

 

 

 

 

 

 

 

By:

Citadel Investment Group, L.L.C.,

 

 

CITADEL EQUITY FUND LTD.

 

 

its General Partner

 

 

 

 

 

 

 

 

By:

Citadel Limited Partnership,

 

By:

/s/ Matthew B. Hinerfeld

 

 

 

its Portfolio Manager

 

 

Matthew B. Hinerfeld, Managing

 

 

 

 

 

 

Director and Deputy General Counsel

 

 

By:

Citadel Investment Group, L.L.C.,

 

 

 

 

 

 

its General Partner

 

CITADEL WELLINGTON LLC

 

 

 

 

 

 

 

 

 

By:

/s/ Matthew B. Hinerfeld

 

By:

Citadel Limited Partnership,

 

 

 

Matthew B. Hinerfeld, Managing

 

 

its Managing Member

 

 

 

Director and Deputy General Counsel

 

 

 

 

 

 

 

 

By:

Citadel Investment Group, L.L.C.,

 

 

CITADEL DERIVATIVES GROUP LLC

 

 

its General Partner

 

 

 

 

 

 

 

 

By:

Citadel Limited Partnership,

 

By:

/s/ Matthew B. Hinerfeld

 

 

 

its Managing Member

 

 

Matthew B. Hinerfeld, Managing

 

 

 

 

 

 

Director and Deputy General Counsel

 

 

By:

Citadel Investment Group, L.L.C.,

 

 

 

 

 

 

its General Partner

 

CITADEL CREDIT PRODUCTS LTD.

 

 

 

 

 

 

 

 

 

By:

/s/ Matthew B. Hinerfeld

 

By:

Citadel Limited Partnership,

 

 

 

Matthew B. Hinerfeld, Managing

 

 

its Portfolio Manager

 

 

 

Director and Deputy General Counsel

 

 

 

 

 

 

 

 

By:

Citadel Investment Group, L.L.C.,

 

 

 

 

 

 

its General Partner

 

 

 

 

 

 

 

 

 

 

 

 

By:

/s/ Matthew B. Hinerfeld

 

 

 

 

 

 

Matthew B. Hinerfeld, Managing

 

 

 

 

 

 

Director and Deputy General Counsel

 

 

 

 

 

 

Page 14 of 14