Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
DENNY JAMES M
  2. Issuer Name and Ticker or Trading Symbol
GILEAD SCIENCES INC [GILD]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
333 LAKESIDE DRIVE
3. Date of Earliest Transaction (Month/Day/Year)
03/06/2007
(Street)

FOSTER CITY, CA 94404
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 03/06/2007   M   10,000 A $ 5.1329 69,600 D  
Common Stock 03/06/2007   M   13,600 A $ 5.1329 83,200 D  
Common Stock 03/06/2007   M   16,400 A $ 6.7657 99,600 D  
Common Stock 03/06/2007   S   101 D $ 70.35 99,499 D  
Common Stock 03/06/2007   S   15 D $ 70.4 99,484 D  
Common Stock 03/06/2007   S   400 D $ 70.42 99,084 D  
Common Stock 03/06/2007   S   84 D $ 70.43 99,000 D  
Common Stock 03/06/2007   S   1,730 D $ 70.45 97,270 D  
Common Stock 03/06/2007   S   100 D $ 70.46 97,170 D  
Common Stock 03/06/2007   S   100 D $ 70.47 97,070 D  
Common Stock 03/06/2007   S   435 D $ 70.48 96,635 D  
Common Stock 03/06/2007   S   1,400 D $ 70.49 95,235 D  
Common Stock 03/06/2007   S   35 D $ 70.5 95,200 D  
Common Stock 03/06/2007   S   1,220 D $ 70.51 93,980 D  
Common Stock 03/06/2007   S   1,200 D $ 70.52 92,780 D  
Common Stock 03/06/2007   S   600 D $ 70.53 92,180 D  
Common Stock 03/06/2007   S   200 D $ 70.54 91,980 D  
Common Stock 03/06/2007   S   1,200 D $ 70.55 90,780 D  
Common Stock 03/06/2007   S   2,900 D $ 70.57 87,880 D  
Common Stock 03/06/2007   S   2,115 D $ 70.58 85,765 D  
Common Stock 03/06/2007   S   600 D $ 70.59 85,165 D  
Common Stock 03/06/2007   S   1,820 D $ 70.6 83,345 D  
Common Stock 03/06/2007   S   200 D $ 70.61 83,145 D  
Common Stock 03/06/2007   S   400 D $ 70.62 82,745 D  
Common Stock 03/06/2007   S   500 D $ 70.63 82,245 D  
Common Stock 03/06/2007   S   900 D $ 70.64 81,345 D  
Common Stock 03/06/2007   S   7,400 D $ 70.65 73,945 D  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Qualified Stock Option (right to buy) $ 5.1329 03/06/2007   M     23,600   (1) 01/01/2009 Common Stock 23,600 $ 0 0 D  
Non-Qualified Stock Option (right to buy) $ 6.7657 03/06/2007   M     16,400   (2) 01/02/2010 Common Stock 16,400 $ 0 55,600 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
DENNY JAMES M
333 LAKESIDE DRIVE
FOSTER CITY, CA 94404
  X      

Signatures

 /s/ James M. Denny   03/07/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Options vested quarterly over a period of five years beginning January 2, 1999, the date of grant.
(2) Options vested quarterly over a period of five years beginning January 3, 2000, the date of grant.
 
Remarks:
The exercise and sale transactions reported in this Form 4 are made persuant to a Rule 10b5-1 trading plan established by Mr. Denny on August 17, 2004. The plan has since been amended and restated on August 18, 2005.  These transactions are being reported are being reported on a two-part Form 4 due to space limitations.  This is Part 1 of 2.

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