UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(AMENDMENT NO. ___)*
EXACT SCIENCES CORPORATION
(Name of Issuer)
COMMON STOCK, PAR VALUE $.01
(Title of Class of Securities)
30063P105
(CUSIP Number)
SEPTEMBER 14, 2010
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:
[_] Rule 13d-1(b)
[X] Rule 13d-1(c)
[_] Rule 13d-1(d)
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
PERSONS WHO ARE TO RESPOND TO THE COLLECTION OF INFORMATION CONTAINED IN THIS
FORM ARE NOT REQUIRED TO RESPOND UNLESS THE FORM DISPLAYS A CURRENTLY VALID OMB
CONTROL NUMBER.
SEC 1745 (12-02)
13G Page 2 of 7 Pages
CUSIP No. 30063P105
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1. NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
PERCEPTIVE ADVISORS LLC
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2. CHECK THE APPROPRIATE BOX IF A GROUP* (a) [ ]
(b) [ ]
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3. SEC USE ONLY
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4. CITIZENSHIP OR PLACE OF ORGANIZATION
DELAWARE
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------------------- ---- -------------------------------------------- --------------------------------------------
NUMBER OF
SHARES 5. SOLE VOTING POWER 0
------------------- ---- -------------------------------------------- --------------------------------------------
BENEFICIALLY
OWNED BY 6. SHARED VOTING POWER 2,028,289
------------------- ---- -------------------------------------------- --------------------------------------------
EACH
REPORTING 7. SOLE DISPOSITIVE POWER 0
------------------- ---- -------------------------------------------- --------------------------------------------
PERSON WITH:
8. SHARED DISPOSTIVE POWER 2,028,289
------------------- ---- -------------------------------------------- --------------------------------------------
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9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 2,028,289
--------- ------------------------------------------------------------------------- ------------------------------
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10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) [ ]
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11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 5.0%
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12. TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) IA
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13G Page 3 of 7 Pages
CUSIP No. 30063P105
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13. NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
JOSEPH EDELMAN
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14. CHECK THE APPROPRIATE BOX IF A GROUP* (a) [ ]
(b) [ ]
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15. SEC USE ONLY
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16. CITIZENSHIP OR PLACE OF ORGANIZATION
UNITED STATES OF AMERICA
--------- --------------------------------------------------------------------------------------------------------
------------------- ---- -------------------------------------------- --------------------------------------------
NUMBER OF
SHARES 17. SOLE VOTING POWER 0
------------------- ---- -------------------------------------------- --------------------------------------------
BENEFICIALLY
OWNED BY 18. SHARED VOTING POWER 2,028,289
------------------- ---- -------------------------------------------- --------------------------------------------
EACH
REPORTING 19. SOLE DISPOSITIVE POWER 0
------------------- ---- -------------------------------------------- --------------------------------------------
PERSON WITH:
20. SHARED DISPOSTIVE POWER 2,028,289
------------------- ---- -------------------------------------------- --------------------------------------------
--------- ------------------------------------------------------------------------- ------------------------------
21. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 2,028,289
--------- ------------------------------------------------------------------------- ------------------------------
--------- --------------------------------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS) [ ]
--------------------------------------------------------------------------------------------------------
--------- ------------------------------------------------------------------------- ------------------------------
23. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 5.0%
--------- ------------------------------------------------------------------------- ------------------------------
24. TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) IN
--------- ------------------------------------------------------------------------- ------------------------------
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13G Page 4 of 7 Pages
CUSIP No. 30063P105
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ITEM 1.
(a) Name of Issuer: Exact Sciences Corporation
441 Charmany Drive
(b) Address of Issuer's Principal Executive Offices: Madison WI 53719
ITEM 2.
This Schedule 13G (the "Schedule") is being filed
with respect to shares of Common Stock (as
defined below) of Exact Sciences Corporation (the
(a) Name of Person Filing: "Issuer") which are beneficially owned by
Perceptive Advisors LLC and Joseph Edelman
(together, the "Reporting Persons"). See Item 4
below.
(b) Address of Principal Perceptive Advisors LLC
Business Office or, if none, 499 Park Avenue, 25th Floor
Residence: New York, NY 10022
(c) Citizenship: Perceptive Advisors LLC is a Delaware
limited liability company and
Joseph Edelman is a United States Citizen.
(d) Title of Class Securities: of Common Stock, par value $.01 (the "Common Stock")
(e) CUSIP Number: 30063P105
ITEM 3 IF THIS STATEMENT IS FILED PURSUANT TO ss.ss.240.13D-1(B) OR
240.13D-2(B) OR (C), CHECK WHETHER THE ITEM 3. PERSON FILING IS A:
(a) [ ] Broker or dealer registered under section 15 of the Act (15 U.S.C.
78o).
(b) [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).
(c) [ ] Insurance company as defined in section 3(a)(19) of the Act (15
U.S.C. 78c).
(d) [ ] Investment company registered under section 8 of the Investment
Company Act of 1940 (15 U.S.C 80a-8).
(e) [ ] An investment adviser in accordance with
ss.240.13d-1(b)(1)(ii)(E);
(f) [ ] An employee benefit plan or endowment fund in accordance with
ss.240.13d-1(b)(1)(ii)(F);
(g) [ ] A parent holding company or control person in accordance with ss.
240.13d-1(b)(1)(ii)(G);
(h) [ ] A savings associations as defined in Section 3(b) of the Federal
Deposit Insurance Act (12 U.S.C. 1813);
(i) [ ] A church plan that is excluded from the definition of an
investment company under section 3(c)(14) of the Investment Company
Act of 1940 (15 U.S.C. 80a-3); (j) [ ] Group, in accordance with
ss.240.13d-1(b)(1)(ii)(J).
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13G Page 5 of 7 Pages
CUSIP No. 30063P105
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OWNERSHIP.
ITEM 4.
Provide the following information regarding the aggregate number and
percentage of the class of securities of the issuer identified in Item 1.
The Reporting Persons beneficially own 2,028,289
shares of Common Stock held by a private
investment fund to which Perceptive Advisors LLC
(a) Amount beneficially owned: serves as the investment manager. Mr. Edelman
is the managing member of Perceptive Advisors LLC.
(b) Percent of class: The beneficial ownership of 5.0% is based on the
2,028,289 outstanding shares of Common Stock of
the Issuer, as disclosed on the Issuer's Form
10-Q filed with the SEC on August 8, 2010.
(c) Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
0
(ii) Shared power to vote or to direct the vote:
2,028,289
(iii) Sole power to dispose or to direct the disposition of: 0
(iv) Shared power to dispose or to direct the disposition of: 2,028,289
ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS
If this statement is being filed to report the fact that as of the date hereof
the reporting person has ceased to be the beneficial owner of more than five
percent of the class of securities, check the following [ ].
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13G Page 6 of 7 Pages
CUSIP No. 30063P105
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ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON
As referred to in Item 4, other persons have the right to receive and the power
to direct the receipt of dividends from, and the proceeds from the sale of,
certain of the shares reported herein. In that regard, Mr. Edelman is the
managing member of Perceptive Advisors LLC, the investment manager of a private
investment fund. Accordingly, the private investment fund has the right to
receive and the power to direct the receipt of, dividends and the proceeds from
the sale of the shares reported herein that are held through the private
investment fund.
ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE
SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY OR CONTROL PERSON.
Not applicable.
ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.
Not applicable.
ITEM 9. NOTICE OF DISSOLUTION OF GROUP.
Not applicable.
ITEM 10. CERTIFICATION
The following certification shall be included if the statement is
filed pursuant to ss.240.13d-1(b):
By signing below I certify that, to the best of my knowledge and
belief, the securities
(a) referred to above were acquired and are held in the ordinary
course of business and were not acquired and are not held for the
purpose of or with the effect of changing or influencing the
control of the issuer of the securities and were not acquired and
are not held in connection with or as a participant in any
transaction having that purpose or effect. [X]
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13G Page 7 of 7 Pages
CUSIP No. 30063P105
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SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.
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September 20, 2010
Date
PERCEPTIVE ADVISORS LLC
/s/ Joseph Edelman
Signature
Joseph Edelman/Managing Member
Name/Title
September 20, 2010
Date
/s/ Joseph Edelman
Signature
Joseph Edelman
Name/Title
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The original statement shall be signed by each person on whose behalf the
statement is filed or his authorized representative. If the statement is signed
on behalf of a person by his authorized representative other than an executive
officer or general partner of the filing person, evidence of the
representative's authority to sign on behalf of such person shall be filed with
the statement, provided, however, that a power of attorney for this purpose
which is already on file with the Commission may be incorporated by reference.
The name and any title of each person who signs the statement shall be typed or
printed beneath his signature.
NOTE: Schedules filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See ss.240.13d-7 for other
parties for whom copies are to be sent.
ATTENTION: INTENTIONAL MISSTATEMENTS OR OMISSIONS OF FACT CONSTITUTE FEDERAL
CRIMINAL VIOLATIONS (SEE 18 U.S.C. 1001)