UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM N-Q

QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED
MANAGEMENT INVESTMENT COMPANIES

Investment Company Act file number 811- 21202

John Hancock Preferred Income Fund II
(Exact name of registrant as specified in charter)

601 Congress Street, Boston, Massachusetts 02210
(Address of principal executive offices) (Zip code)

Alfred E. Ouellette, Senior Counsel and Assistant Secretary

601 Congress Street

Boston, Massachusetts 02210

(Name and address of agent for service)

Registrant's telephone number, including area code:  617-663-4324 
 
Date of fiscal year end:  July 31 
  
Date of reporting period:  October 31, 2007 

ITEM 1. SCHEDULE OF INVESTMENTS




John Hancock
Preferred Income Fund II
Securities owned by the Fund on
October 31, 2007 (unaudited)

    Interest  Maturity  Credit  Par value   
Issuer, description    rate  date  rating (A)  (000)  Value 

Bonds 4.21%            $20,194,232 
(Cost $20,533,892)             
 
Electric Utilities 2.02%            9,663,085 

Black Hills Corp.,             
Note    6.500%  05-15-13  BBB-  $5,000  4,996,865 
Entergy Gulf States, Inc.,             
1st Mtg Bond    6.200  07-01-33  BBB+  5,000  4,666,220 
 
Gas Utilities 2.20%            10,531,147 

Southern Union Co.,             
Jr Sub Note, Ser A    7.200  11-01-66  BB  10,550  10,531,147 
   
    Interest  Maturity  Credit  Par value   
Issuer, description    rate  date  rating (A)  (000)  Value 

Capital preferred securities  15.03%          $72,001,405 
(Cost $681,007,774)             
   
Asset Management & Custody Banks  1.02%          4,873,604 

BNY Capital, Ser B    7.97%  12-31-26  A-  $4,700  4,873,604 
 
Diversified Banks 0.82%            3,910,000 

Lloyds TSB Bank Plc (United Kingdom) (F)  6.90  11-29-49  A+  4,000  3,910,000 
 
Electric Utilities 5.28%            25,274,833 

DPL Capital Trust II    8.125  09-01-31  BB+  22,150  25,274,833 
 
Gas Utilities 4.88%            23,396,024 

KN Capital Trust I, Ser B    8.56  04-15-27  B-  14,000  13,720,000 
KN Capital Trust III    7.63  04-15-28  B-  10,673  9,676,024 
 
Multi-Utilities 3.04%            14,546,944 

Dominion Resources Capital Trust I    7.83  12-01-27  BB+  8,450  8,818,834 
Dominion Resources Capital Trust III    8.40  01-15-31  BB+  5,000  5,728,110 
 
Issuer          Shares  Value 

Common stocks 2.47%             $11,836,690 
(Cost $9,857,727)             
   
Electric Utilities 1.08%            5,195,890 

Great Plains Energy, Inc.          174,125  5,195,890 
 
Integrated Oil & Gas 0.49%            2,339,700 

BP Plc (ADR) (United Kingdom) (F)          30,000  2,339,700 

Page 1


John Hancock
Preferred Income Fund II
Securities owned by the Fund on
October 31, 2007 (unaudited)

Multi-Utilities 0.90%        4,301,100 

Alliant Energy Corp.      90,000  3,600,000 
CH Energy Group, Inc.      15,000  701,100 
     
    Credit     
Issuer, description    rating (A)  Shares  Value 

Preferred stocks 126.80%      $607,528,293 
(Cost $636,789,036)         
  
Agricultural Products  2.98%      14,265,008 

Ocean Spray Cranberries, Inc., 6.25%,       
Ser A (S)    BB+  160,000  14,265,008 
 
Automobile Manufacturers 2.44%      11,680,211 

General Motors Corp., 7.25%, Ser 04-15-41  B-  77,900  1,417,001 
General Motors Corp., 7.25%, Ser 07-15-41  B-  50,500  927,685 
General Motors Corp., 7.25%, Ser 02-15-52  B-  442,300  7,974,669 
General Motors Corp., 7.375%, Ser 10-01-51  B-  73,125  1,360,856 
  
Broadcasting & Cable TV 4.56%      21,872,328 

CBS Corp., 6.75%    BBB  122,800  2,894,396 
Comcast Corp., 6.625%    BBB+  118,500  2,752,755 
Comcast Corp., 7.00%    BBB+  40,000  992,800 
Comcast Corp., 7.00%, Ser B  BBB+  615,201  15,232,377 
 
Consumer Finance 4.21%      20,167,131 

HSBC Finance Corp., 6.00%  AA-  72,200  1,664,210 
HSBC Finance Corp., 6.36%, Depositary       
Shares, Ser B    A  143,200  3,521,288 
HSBC Finance Corp., 6.875%  AA-  349,100  8,744,955 
SLM Corp., 6.00%    BBB+  196,800  3,495,168 
SLM Corp., 6.97%, Ser A  BBB-  61,400  2,741,510 
 
Diversified Banks 8.45%      40,486,814 

BAC Capital Trust II, 7.00%  A+  22,400  551,264 
BAC Capital Trust IV, 5.875%  A+  51,150  1,116,605 
Barclays Bank Plc, 7.10%, Ser 3 (United       
Kingdom) (F)    A+  100,000  2,530,000 
Fleet Capital Trust VIII, 7.20%  A+  344,700  8,624,394 
HSBC Holdings Plc, 6.20%, Ser A (United       
Kingdom) (F)    A  254,600  5,733,592 
Republic New York Corp., 6.25%, Ser HSBC  A  50,000  1,143,000 
Royal Bank of Scotland Group Plc, 5.75%,       
Ser L (United Kingdom) (F)  A  450,500  9,492,035 
Royal Bank of Scotland Group Plc, 7.25%,       
Ser T (United Kingdom) (F)  A  26,000  662,220 
Santander Finance Preferred SA,       
Unipersonal, 6.41%, Ser 1 (Spain) (F)  A+  225,000  5,220,000 
USB Capital VIII, 6.35%, Ser 1  A+  83,000  1,882,440 
Wells Fargo Capital Trust IV, 7.00%  AA-  140,800  3,531,264 

Page 2


John Hancock
Preferred Income Fund II
Securities owned by the Fund on
October 31, 2007 (unaudited)

 
Diversified Financial Services 13.57%      65,009,841 

ABN AMRO Capital Funding Trust V, 5.90%  A  403,600  8,608,788 
ABN AMRO Capital Funding Trust VII, 6.08%  A  365,000  7,942,400 
Citigroup Capital VII, 7.125%  A+  364,200  9,112,284 
Citigroup Capital VIII, 6.95%  A+  598,000  14,692,860 
DB Capital Funding VIII, 6.375%  A+  414,700  9,629,334 
DB Capital Trust II, 6.55%  A+  357,500  8,562,125 
JPMorgan Chase Capital X, 7.00%, Ser J  A  259,000  6,462,050 
  
Electric Utilities 19.62%      94,005,089 

Duquesne Light Co., 6.50%  BB  98,450  5,005,572 
Entergy Mississippi, Inc., 7.25%  A-  109,000  2,746,800 
FPC Capital I, 7.10%, Ser A  BBB-  602,003  15,080,175 
FPL Group Capital Trust I, 5.875%  BBB+  441,800  10,028,860 
FPL Group Capital, Inc., 7.45%, Ser E  BBB+  60,000  1,557,000 
Georgia Power Capital Trust VII, 5.875%  BBB+  116,500  2,573,485 
HECO Capital Trust III, 6.50%  BB+  130,000  3,088,800 
Interstate Power & Light Co., 8.375%, Ser B  Baa2  700,000  21,070,000 
NSTAR Electric Co., 4.78%  A-  15,143  1,309,870 
PPL Electric Utilities Corp., 6.25%,       
Depositary Shares  BBB  130,000  3,327,194 
PPL Energy Supply, LLC, 7.00%  BBB  638,570  16,060,036 
Southern California Edison Co., 6.00%,       
Ser C  BBB-  20,000  1,910,000 
Virginia Power Capital Trust, 7.375%  BB+  310,719  7,777,297 
Westar Energy, Inc., 6.10%  AAA  100,000  2,470,000 
  
Gas Utilities 2.04%      9,778,940 

Southern Union Co., 7.55%  BB  129,500  3,288,005 
Southwest Gas Capital II, 7.70%  BB  258,500  6,490,935 
  
Integrated Telecommunication Services 1.23%      5,892,027 

AT&T, Inc., 6.375%  A  43,100  1,038,279 
Verizon New England, Inc., 7.00%, Ser B  A3  190,717  4,853,748 
  
Investment Banking & Brokerage 12.79%      61,302,737 

Bear Stearns Cos., Inc. (The), 6.15%,       
Depositary Shares, Ser E  BBB+  264,400  12,270,804 
Lehman Brothers Holdings Capital Trust III,       
6.375%, Ser K  A-  177,000  3,993,120 
Lehman Brothers Holdings Capital Trust V,       
6.00%, Ser M  A-  46,600  985,124 
Lehman Brothers Holdings, Inc., 5.94%,       
Depositary Shares, Ser C  A-  145,200  6,679,200 
Merrill Lynch Preferred Capital Trust III,       
7.00%  A  360,400  8,775,740 
Merrill Lynch Preferred Capital Trust IV,       
7.12%  A  172,200  4,222,344 
Merrill Lynch Preferred Capital Trust V,       
7.28%  A  275,000  6,825,500 
Morgan Stanley Capital Trust III, 6.25%  A  268,779  6,026,025 
Morgan Stanley Capital Trust IV, 6.25%  A  57,000  1,270,530 
Morgan Stanley Capital Trust V, 5.75%  A1  311,500  6,510,350 
Morgan Stanley Capital Trust VI, 6.60%  A  160,000  3,744,000 

Page 3


John Hancock
Preferred Income Fund II
Securities owned by the Fund on
October 31, 2007 (unaudited)

 
Life & Health Insurance 3.15%      15,104,123 

Phoenix Cos., Inc. (The), 7.45%  BBB-  186,200  4,506,040 
PLC Capital Trust IV, 7.25%  BBB+  335,475  8,346,618 
Prudential Plc, 6.50% (United Kingdom) (F)  A-  95,807  2,251,465 
  
Movies & Entertainment 4.22%      20,222,099 

Viacom, Inc., 6.85%  BBB  834,245  20,222,099 
  
Multi-Line Insurance 11.75%      56,299,532 

Aegon NV, 6.375% (Netherlands) (F)  A-  355,000  8,157,900 
Aegon NV, 6.50% (Netherlands) (F)  A-  44,100  1,018,269 
ING Groep NV, 7.05% (Netherlands) (F)  A  774,700  19,290,030 
ING Groep NV, 7.375% (Netherlands) (F)  A  88,000  2,238,720 
MetLife, Inc., 6.50%, Ser B  BBB  1,029,550  25,594,613 
  
Multi-Utilities 11.89%      56,955,562 

Baltimore Gas & Electric Co., 6.99%,       
Ser 1995  Ba1  39,870  4,111,594 
BGE Capital Trust II, 6.20%  BBB-  672,200  14,895,952 
DTE Energy Trust I, 7.80%  BB+  313,000  7,853,170 
PNM Resources, Inc., 6.75%, Conv  BBB-  240,700  10,817,058 
PSEG Funding Trust II, 8.75%  BB+  680,000  17,149,600 
Public Service Electric & Gas Co., 4.18%,       
Ser B  BB+  7,900  612,250 
South Carolina Electric & Gas Co., 6.52%  Baa1  15,000  1,515,938 
 
Oil & Gas Exploration & Production 6.66%      31,892,422 

Chesapeake Energy Corp., 6.25%, Conv (G)  B+  4,850  1,532,697 
Devon Energy Corp., 6.49%, Ser A  BB+  32,355  3,286,055 
Nexen, Inc., 7.35% (Canada) (F)  BB+  1,096,100  27,073,670 
 
Real Estate Management & Development 4.90%      23,464,236 

Duke Realty Corp., 6.50%, Depositary       
Shares, Ser K  BBB  110,000  2,442,000 
Duke Realty Corp., 6.60%, Depositary       
Shares, Ser L  BBB  109,840  2,452,727 
Duke Realty Corp., 6.625%, Depositary       
Shares, Ser J  BBB  449,400  10,124,982 
Public Storage, Inc., 6.45%, Depositary       
Shares, Ser X  BBB+  30,000  653,400 
Public Storage, Inc., 7.50%, Depositary       
Shares, Ser V  BBB+  307,100  7,791,127 
  
Regional Banks 3.72%      17,814,597 

PFGI Capital Corp., 7.75%  A  686,000  17,814,597 

Page 4


John Hancock
Preferred Income Fund II
Securities owned by the Fund on
October 31, 2007 (unaudited)

 
Reinsurance 0.17%            792,000 

RenaissanceRe Holdings Ltd., 6.08%, Ser C           
(Bermuda) (F)        BBB  40,000  792,000 
 
Specialized Finance 1.19%          5,705,982 

CIT Group, Inc., 6.35%, Ser A      BBB+  100,000  2,230,000 
Repsol International Capital Ltd., 7.45%,           
Ser A (Cayman Islands) (F)      BB+  136,313  3,475,982 
Thrifts & Mortgage Finance 0.61%          2,906,970 

Sovereign Capital Trust V, 7.75%      BB+  115  2,906,970 
Wireless Telecommunication Services 6.66%          31,910,644 

Telephone & Data Systems, Inc., 6.625%      BB+  155,000  3,123,250 
Telephone & Data Systems, Inc., 7.60%,           
Ser A        BB+  665,967  15,723,481 
United States Cellular Corp., 7.50%      BB+  559,243  13,063,913 
    
      Number of  Exercise     Expiration  
Issuer      contracts  price  date  Value 

Purchased options  0.04%          $171,360 
(Cost $158,559)             
 
Options - Puts 0.04%            171,360 

iShares S&P SmallCap Index Fund    952  $88  03-24-08  171,360 
   
    Interest  Maturity  Credit  Par value   
Issuer, description    rate  date  rating (A)  (000)  Value 

Short-term investments 3.44%          $16,500,000 
(Cost $16,500,000)             
 
Government U.S. Agency  3.44%          16,500,000 

Federal Home Loan Bank,             
Discount Note    4.40% (Y)  11-01-07  AAA  $16,500  16,500,000 

Page 5


John Hancock
Preferred Income Fund II
Securities owned by the Fund on
October 31, 2007 (unaudited)

Total investments (Cost $1,364,846,988) 151.99%    $728,231,980 
 
Other assets and liabilities, net 1.37%    $6,557,161 
 
Fund preferred shares, at liquidation value (53.36%)    ($255,658,094) 
 
Total net assets applicable to common shareholders  100.00%  $479,131,047 

The percentage shown for each investment
category is the total value of that category, as
a percentage of the net assets applicable to
common shareholders.

Page 6


John Hancock
Preferred Income Fund II
Notes to Schedule of Investments
October 31, 2007 (unaudited)

ADR American Depositary Receipt

(A) Credit ratings are unaudited and are rated by Moody's Investors Service where Standard & Poor's ratings are not available unless indicated otherwise.

(F) Parenthetical disclosure of a foreign country in the security description represents country of a foreign issuer; however, security is U.S. dollar-denominated.

(G) Security rated internally by John Hancock Advisers, LLC.

(S) This security is exempt from registration under Rule 144A of the Securities Act of 1933. Such securities may be resold, normally to qualified institutional buyers, in transactions exempt from registration. Rule 144A securities amounted to $14,265,008 or 2.98% of the net assets applicable to common shareholders as of October 31, 2007.

(Y) Represents current yield as of October 31, 2007.

The cost of investments owned on October 31, 2007, including short-term investments, was $1,364,846,988. Gross unrealized appreciation and depreciation of investments aggregated $15,254,404 and $38,960,868 respectively, resulting in net unrealized depreciation of $23,706,464.

Notes to Schedule of Investments - Page 1


John Hancock
Preferred Income Fund II
Interest rate swap contracts
October 31, 2007 (unaudited)

  Rate type       

Notional  Payments made  Payments received  Termination    Appreciation 
amount  by Fund    by Fund  date    Counterparty  (depreciation) 

 
$63,500,000  2.558% (a)  3-month LIBOR  June 2008  Morgan Stanley  $885,880 

(a) Fixed rate

Interest rate swap contracts


John Hancock
Preferred Income Fund II
Financial futures contracts
October 31, 2007 (unaudited)

  Number of      Appreciation 
Open contracts  contracts  Position  Expiration  (depreciation) 

 
U.S. 10-year Treasury Note  720  Short  Dec 2007  $399,958 

Financial futures contracts


Notes to portfolio of investments

Security valuation

The net asset value of the common shares of the Fund is determined daily as of the close of the New York Stock Exchange (NYSE), normally at 4:00 P.M., Eastern Time. Short-term debt investments that have a remaining maturity of 60 days or less are valued at amortized cost, and thereafter assume a constant amortization to maturity of any discount or premium, which approximates market value. All other securities held by the Fund are valued at the last sale price or official closing price (closing bid price or last evaluated quote if no sale has occurred) as of the close of business on the principal securities exchange (domestic or foreign) on which they trade or, lacking any sales, at the closing bid price. Securities traded only in the over-the-counter market are valued at the last bid price quoted by brokers making markets in the securities at the close of trading. Securities for which there are no such quotations, principally debt securities, are valued based on the valuation provided by an independent pricing service, which utilizes both dealer-supplied and electronic data processing techniques, which take into account factors such as institutional-size trading in similar groups of securities, yield, quality, coupon rate, maturity, type of issue, trading characteristics and other market data.

Other assets and securities for which no such quotations are readily available are valued at fair value as determined in good faith under consistently applied procedures established by and under the general supervision of the Board of Trustees. Generally, trading in non-U.S. securities is substantially completed each day at various times prior to the close of trading on the NYSE. The values of such securities used in computing the net asset value of the Fund’s shares are generally determined as of such times. Occasionally, significant events that affect the values of such securities may occur between the times at which such values are generally determined and the close of the NYSE. Upon such an occurrence, these securities will be valued at fair value as determined in good faith under consistently applied procedures established by and under the general supervision of the Board of Trustees.

Futures

The Fund may purchase and sell financial futures contracts and options on those contracts. The Fund invests in contracts based on financial instruments such as U.S. Treasury Bonds or Notes or on securities indices such as the Standard & Poor’s 500 Index, in order to hedge against a decline in the value of securities owned by the Fund.

Initial margin deposits required upon entering into futures contracts are satisfied by the delivery of specific securities or cash as collateral to the broker (the Funds’ agent in acquiring the futures position). If the position is closed out by taking an opposite position prior to the settlement date of the futures contract, a final determination of variation margin is made, cash is required to be paid to or released by the broker and the Fund realizes a gain or loss.

When the Fund sells a futures contract based on a financial instrument, the Fund becomes obligated to deliver that kind of instrument at an agreed upon date for a specified price. The Fund realizes a gain or loss depending on whether the price of an offsetting purchase is less or more than the price of the initial sale or on whether the price of an offsetting sale is more or less than the price of the initial purchase. The Fund could be exposed to risks if it could not close out futures positions because of an illiquid secondary market or the inability of counterparties to meet the terms of their contracts. Futures contracts are valued at the quoted daily settlement prices established by the exchange on which they trade.

Notes to Schedule of Investments - Page 2


Swap contracts

The Fund may enter into swap transactions in order to hedge the value of the Fund’s portfolio against interest rate fluctuations or to enhance the Fund’s income. Interest rate swaps represent an agreement between two counterparties to exchange cash flows based on the difference in the two interest rates, applied to the notional principal amount for a specified period. The payment flows are usually netted against each other, with the difference being paid by one party to the other. The Fund settles accrued net receivable or payable under the swap contracts on a periodic basis.

The Fund records changes in the value of the swaps as unrealized gains or losses on swap contracts. Net periodic payments accrued, but not yet received (paid) are included in change in the unrealized appreciation/ depreciation on the Statement of Operations.

Swap contracts are subject to risks related to the counterparty’s ability to perform under the contract, and may decline in value if the counterparty’s creditworthiness deteriorates. The risks may arise from unanticipated movement in interest rates. The Fund may also suffer losses if it is unable to terminate outstanding swap contracts or reduce its exposure through offsetting transactions.

Notes to Schedule of Investments - Page 3




ITEM 2. CONTROLS AND PROCEDURES.

(a) Based upon their evaluation of the registrant's disclosure controls and procedures as conducted within 90 days of the filing date of this Form N-Q, the registrant's principal executive officer and principal accounting officer have concluded that those disclosure controls and procedures provide reasonable assurance that the material information required to be disclosed by the registrant on this report is recorded, processed, summarized and reported within the time periods specified in the Securities and Exchange Commission's rules and forms.

(b) There were no changes in the registrant's internal control over financial reporting that occurred during the registrant's last fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting.

ITEM 3. EXHIBITS.

Separate certifications for the registrant's principal executive officer and principal accounting officer, as required by Rule 30a-2(a) under the Investment Company Act of 1940, are attached.


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

John Hancock Preferred Income Fund II

By: /s/ Keith F. Hartstein
-------------------------------------
Keith F. Hartstein
President and
Chief Executive Officer

Date: December 19, 2007

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By: /s/ Keith F. Hartstein
-------------------------------------
Keith F. Hartstein
President and
Chief Executive Officer

Date: December 19, 2007

By: /s/ Charles A. Rizzo
-------------------------------------
Charles A. Rizzo
Chief Financial Officer

Date: December 19, 2007