Sign In  |  Register  |  About Santa Clara  |  Contact Us

Santa Clara, CA
September 01, 2020 1:39pm
7-Day Forecast | Traffic
  • Search Hotels in Santa Clara

  • CHECK-IN:
  • CHECK-OUT:
  • ROOMS:

Understanding Agitation That May Happen with Dementia Due to Alzheimer's Disease

SPONSORED CONTENT -- (StatePoint) This article is sponsored by Otsuka America Pharmaceutical, Inc. and Lundbeck, for which Dr. George Grossberg is a paid consultant.

June is National Alzheimer’s and Brain Awareness Month, which represents an opportunity to reflect on the importance of brain health and to help raise awareness for Alzheimer’s dementia, a disease that affects an estimated 6.7 million Americans nationwide.

In addition to educating the public on the signs and symptoms of Alzheimer’s disease, this annual awareness month aims to support and empower both patients and caregivers by encouraging them to speak to a healthcare professional about critical treatment and resources. This is also a time to take note of symptoms they may not otherwise think to share with healthcare providers, such as the symptoms of agitation that may happen with dementia due to Alzheimer’s disease.

About half or more Alzheimer’s dementia patients experience symptoms of agitation. Agitation is a common neuropsychiatric symptom that can significantly impact the quality of life for those navigating the complexities of this condition.

“People don’t always recognize that agitation that may happen with dementia due to Alzheimer’s disease can be treated separately,” says Dr. Grossberg. “It’s crucial for caretakers to spot key signs and symptoms of behaviors associated with agitation, such as cursing, hitting, wandering, repetitive movements or questions, or resisting help, and to speak to a healthcare professional about these behaviors.”

There are ways to manage the condition, such as creating a simple routine, being mindful of potential triggers (loud noises, perceived threats), maintaining a calm environment, identifying sources of comfort, and encouraging light physical activity. Another tip is to prepare a list of ongoing symptoms and questions and to share them with a healthcare professional. Keep in mind that even if behavioral changes are slight, it’s important to report any changes. Until recently, there were no FDA-approved treatments for agitation that may happen with dementia due to Alzheimer’s disease, but one just became available.

When speaking to a healthcare professional, ask about REXULTI® (brexipiprazole) – the first and only FDA-approved pharmacological treatment for agitation that may happen with dementia due to Alzheimer’s disease. REXULTI should not be used as an “as needed” treatment for agitation that may happen with dementia due to Alzheimer’s disease.

Read the Important Safety Information, including BOXED WARNING, regarding an increased risk of death in elderly people with dementia-related psychosis, below.

“National Alzheimer’s and Brain Awareness Month represents a great opportunity to remind, educate and empower patients, caregivers and healthcare providers to maintain open lines of communication that will ensure they’re proactively managing the best possible care plan as the patient’s condition evolves,” says Dr. Grossberg. “While agitation that may happen with dementia due to Alzheimer’s disease places a heavy stress on both the patient and caregiver, it’s important that they are aware of treatment options that may help address the symptoms of this challenging condition.”

Dr. Grossberg also advises patients to engage their healthcare team if they have any concerns or notice any changes in their overall brain health.

INDICATION and IMPORTANT SAFETY INFORMATION for
REXULTI® (brexpiprazole)

INDICATION:

REXULTI is a prescription medicine used to treat agitation that may happen with dementia due to Alzheimer’s disease

REXULTI should not be used as an “as needed” treatment for agitation that may happen with dementia due to Alzheimer’s disease.

IMPORTANT SAFETY INFORMATION:

Increased risk of death in elderly people with dementia-related psychosis. Medicines like REXULTI can raise the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia). REXULTI is not approved for the treatment of people with dementia-related psychosis without agitation that may happen with dementia due to Alzheimer’s disease.

Do not take REXULTI if you are allergic to brexpiprazole or any of the ingredients in REXULTI.

REXULTI may cause serious side effects, including:

Cerebrovascular problems, including stroke, in elderly people with dementia-related psychosis that can lead to death.

Neuroleptic malignant syndrome (NMS) is a serious condition that can lead to death. Call your healthcare provider or go to the nearest hospital emergency room right away if you have some or all of the following signs and symptoms of NMS: high fever; changes in your pulse, blood pressure, heart rate, and breathing; stiff muscles; confusion; increased sweating

• Uncontrolled body movements (tardive dyskinesia). REXULTI may cause movements that you cannot control in your face, tongue, or other body parts. Tardive dyskinesia may not go away, even if you stop taking REXULTI. Tardive dyskinesia may also start after you stop taking REXULTI.

• Problems with your metabolism such as:

     • high blood sugar (hyperglycemia) and diabetes. Increases in blood sugar can happen in some people who take REXULTI. Extremely high blood sugar can lead to coma or death. Your healthcare provider should check your blood sugar before you start, or soon after you start REXULTI and then regularly during long term treatment with REXULTI.

Call your healthcare provider if you have any of these symptoms of high blood sugar during treatment with REXULTI:

          • feel very thirsty

          • feel very hungry

          • feel sick to your stomach

          • need to urinate more than usual

          • feel weak or tired

          • feel confused, or your breath smells fruity

     • increased fat levels (cholesterol and triglycerides) in your blood. Your healthcare provider should check the fat levels in your blood before you start, or soon after you start REXULTI, and then periodically during treatment with REXULTI.

     • weight gain. You and your healthcare provider should check your weight before you start and often during treatment with REXULTI.

• Unusual and uncontrollable (compulsive) urges. Some people taking REXULTI have had strong unusual urges, to gamble and gambling that cannot be controlled (compulsive gambling). Other compulsive urges include sexual urges, shopping, and eating or binge eating. If you or your family members notice that you are having new or unusual strong urges or behaviors, talk to your healthcare provider.

• Low white blood cell count. Your healthcare provider may do blood tests during the first few months of treatment with REXULTI.

• Decreased blood pressure (orthostatic hypotension) and fainting. You may feel dizzy, lightheaded or pass out (faint) when you rise too quickly from a sitting or lying position.

• Falls. REXULTI may make you sleepy or dizzy, may cause a decrease in your blood pressure when changing position (orthostatic hypotension), and can slow your thinking and motor skills which may lead to falls that can cause fractures or other injuries.

Seizures (convulsions).

• Problems controlling your body temperature so that you feel too warm. Do not become too hot or dehydrated during treatment with REXULTI. Do not exercise too much. In hot weather, stay inside in a cool place if possible. Stay out of the sun. Do not wear too much clothing or heavy clothing. Drink plenty of water.

• Difficulty swallowing that can cause food or liquid to get into your lungs.

• Sleepiness, drowsiness, feeling tired, difficulty thinking and doing normal activities. Do not drive a car, operate machinery, or do other dangerous activities until you know how REXULTI affects you. REXULTI may make you feel drowsy.

Before taking REXULTI, tell your healthcare provider about all of your medical conditions, including if you:

• have or have had heart problems or a stroke

• have or have had low or high blood pressure

• have or have had diabetes or high blood sugar or a family history of diabetes or high blood sugar. Your healthcare provider should check your blood sugar before you start REXULTI and during treatment with REXULTI.

• have or have had high levels of total cholesterol, LDL cholesterol, or triglycerides, or low levels of HDL cholesterol

• have or have had seizures (convulsions)

• have or have had kidney or liver problems

• have or have had a low white blood cell count

• are pregnant or plan to become pregnant. REXULTI may harm your unborn baby. Taking REXULTI during your third trimester of pregnancy may cause your baby to have abnormal muscle movements or withdrawal symptoms after birth. Talk to your healthcare provider about the risk to your unborn baby if you take REXULTI during pregnancy.

     • Tell your healthcare provider if you become pregnant or think you are pregnant during treatment with REXULTI.

     • There is a pregnancy exposure registry for women who are exposed to REXULTI during pregnancy. If you become pregnant during treatment with REXULTI, talk to your healthcare provider about registering with the National Pregnancy Registry for Atypical Antipsychotics. You can register by calling 1-866-961-2388 or visit http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/.

• are breastfeeding or plan to breastfeed. It is not known if REXULTI passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with REXULTI.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. REXULTI and other medicines may affect each other causing possible serious side effects. REXULTI may affect the way other medicines work, and other medicines may affect how REXULTI works. Your healthcare provider can tell you if it is safe to take REXULTI with your other medicines. Do not start or stop any medicines during treatment with REXULTI without first talking to your healthcare provider.

The most common side effects of REXULTI include weight gain, sleepiness, dizziness, common cold symptoms, and restlessness or feeling like you need to move (akathisia).

These are not all the possible side effects of REXULTI. For more information, ask your healthcare provider or pharmacist.

You are encouraged to report side effects of REXULTI (brexpiprazole). Please contact Otsuka America Pharmaceutical, Inc. at 1-800-438-9927 or FDA at 1-800-FDA-1088 (www.fda.gov/medwatch).

Read FULL PRESCRIBING INFORMATION, including BOXED WARNING, and MEDICATION GUIDE.

Data & News supplied by www.cloudquote.io
Stock quotes supplied by Barchart
Quotes delayed at least 20 minutes.
By accessing this page, you agree to the following
Privacy Policy and Terms and Conditions.
 
 
Copyright © 2010-2020 SantaClara.com & California Media Partners, LLC. All rights reserved.